AbbVie to buy Capstan for up to $2.1 billion in immunology push

- 6/30/2025

</head><body><p>(Reuters) -U.S. drugmaker AbbVie said on Monday it will acquire cell therapy developer Capstan Therapeutics in a cash deal worth up to $2.1 billion, expanding its pipeline with experimental treatments for autoimmune diseases.</p><p>AbbVie has been diversifying its portfolio to make up for a steep decline in the sales of Humira, its flagship rheumatoid arthritis drug that is facing stiff competition.</p><p>Since Humira's patent expiration, AbbVie has spent over $20 billion on acquisitions, including $8.7 billion for neuroscience firm Cerevel, $10.1 billion for cancer drugmaker ImmunoGen and $1.4 billion for Alzheimer's-focused biotech Aliada.</p><p>Under the terms of the agreement, AbbVie will pay up to $2.1 billion in cash to acquire Capstan, subject to certain customary adjustments.</p><p>Capstan develops CAR-T therapies, a type of treatment that uses a patient's own immune cells, specifically T cells, to fight diseases. Its main drug, CPTX2309, is currently in early-stage development for the treatment of autoimmune diseases. </p><p>The drug works by using tiny fat-based particles called lipid nanoparticles to deliver instructions to certain immune cells, which find and remove harmful cells that mistakenly attack the body.</p><p>The deal aims to strengthen AbbVie's already strong position in immunology, building on the success of autoimmune treatments Skyrizi and Rinvoq, which are expected to generate over $31 billion in combined sales by 2027.</p><p> (Reporting by Christy Santhosh in Bengaluru; Editing by Shreya Biswas)</p></body></html></p> <div id="news-wrapper"> <div class="thumbnail additional-resources client-content-image-box"> <div class="box-image" style="background-image: url(/images/home/news.jpg);"></div> <div class="caption"> <h3>Nationwide News</h3> <div> <p><a href='/pr/news-article-detail.aspx?id=155246'>Kneaded culinary academy cooks up solutions for struggling youth</a></p> <p><a href='/pr/news-article-detail.aspx?id=155194'>Better schools in California state prisons</a></p> <p><a href='/pr/news-archive.aspx'>News Archive</a></p> </div> </div> </div> </div> </div> </div> </div> </section> </div>  <footer class="footer">  <div class="clearfix footerInfo"> <div class="container"> <div class="row"> <div class="col-sm-7 col-xs-12"> <div class="footerText"> <a href="http://www.trilogyir.com/" target="_blank" class="footerLogo"><img src="/images/Noc-Logo-white.png" alt="Footer Logo" style="width: 200px;"></a> <div class="genericContent" id="landingPageText"> <p>An online information portal for individuals, families and social service agencies concerned with reentry. 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AbbVie to buy Capstan for up to $2.1 billion in immunology push