AbbVie to buy Capstan for up to $2.1 billion in immunology push

- 6/30/2025

</head><body><p>(Reuters) -U.S. drugmaker AbbVie said on Monday it will acquire cell therapy developer Capstan Therapeutics in a cash deal worth up to $2.1 billion, expanding its pipeline with experimental treatments for autoimmune diseases.</p><p>AbbVie has been diversifying its portfolio to make up for a steep decline in the sales of Humira, its flagship rheumatoid arthritis drug that is facing stiff competition.</p><p>Since Humira's patent expiration, AbbVie has spent over $20 billion on acquisitions, including $8.7 billion for neuroscience firm Cerevel, $10.1 billion for cancer drugmaker ImmunoGen and $1.4 billion for Alzheimer's-focused biotech Aliada.</p><p>Under the terms of the agreement, AbbVie will pay up to $2.1 billion in cash to acquire Capstan, subject to certain customary adjustments.</p><p>Capstan develops CAR-T therapies, a type of treatment that uses a patient's own immune cells, specifically T cells, to fight diseases. Its main drug, CPTX2309, is currently in early-stage development for the treatment of autoimmune diseases. </p><p>The drug works by using tiny fat-based particles called lipid nanoparticles to deliver instructions to certain immune cells, which find and remove harmful cells that mistakenly attack the body.</p><p>The deal aims to strengthen AbbVie's already strong position in immunology, building on the success of autoimmune treatments Skyrizi and Rinvoq, which are expected to generate over $31 billion in combined sales by 2027.</p><p> (Reporting by Christy Santhosh in Bengaluru; Editing by Shreya Biswas)</p></body></html></p> <div id="news-wrapper"> <div class="thumbnail additional-resources client-content-image-box"> <div class="box-image" style="background-image: url(/images/home/news.jpg);"></div> <div class="caption"> <h3>Nationwide News</h3> <div> <p><a href='/mh/news-article-detail.aspx?id=155564'>NJ AG investigating after Fort Lee police shoot woman in ‘mental health 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AbbVie to buy Capstan for up to $2.1 billion in immunology push